HUMANIZATION AND EXPRESSION OF IGG AND IGM ANTIBODIES IN PLANTS AS POTENTIAL DIAGNOSTIC REAGENTS FOR VALLEY FEVER

Humanization and expression of IgG and IgM antibodies in plants as potential diagnostic reagents for Valley Fever

Monoclonal antibodies (mAbs) are important proteins used in many life science applications, from diagnostics to therapeutics.High demand for mAbs for different applications urges the development of rapid and reliable recombinant production platforms.Plants provide a quick and inexpensive system for producing recombinant mAbs.Moreover, when paired w

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Comparative transcriptome analysis of SARS-CoV-2, SARS-CoV, MERS-CoV, and HCoV-229E identifying potential IFN/ISGs targets for inhibiting virus replication

IntroductionSince its Microphone outbreak in December 2019, SARS-CoV-2 has spread rapidly across the world, posing significant threats and challenges to global public health.SARS-CoV-2, together with SARS-CoV and MERS-CoV, is a highly pathogenic coronavirus that contributes to fatal pneumonia.Understanding the similarities and differences at the tr

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